In our study, we observed that the density rate of Ki67 + positive cells was highest in neoplastic transformed A associated with (moderately differentiated G2 endometrioid carcinoma), followed by cases of hyperplastic transformed A and then cases of AE, PE, OE, EPP and ESP, thus demonstrating that the most susceptible cases for transformation in our study are those with A and AE. The gene discussed is MKI67; the disease is endometrioid adenocarcinoma.