Some of them are referred to in the following section, such as the amyloid protein with Alzheimer’s disease, α1-antitrypsin with α1-antitrypsin deficiency (AATD), β-glucocerebrosidase (β-GCases) with Gaucher’s disease, the chloride channel and ENaC with cystic fibrosis, or insulin with diabetes (Table 1). The gene discussed is INS; the disease is diabetes mellitus.