Thus, the functional effects of MYD88L265P include increased NF-κB activity; Janus kinase (JAK)/signal transducer and activator of transcription (STAT) signaling; and the production of proinflammatory cytokines, such as IL-6, IL-10 and interferon (IFN)-β, as well as the enhanced growth and survival of lymphoma cells [23,26]. Here, IL6 is linked to lymphoma.