TGFB1 and metabolic dysfunction-associated steatohepatitis: Consistent with this observation, Oxy210 robustly inhibited the hepatic expression of inflammatory cytokines as well as their plasma levels in a humanized mouse model of NASH without displaying any toxic effects that could have been expected if Oxy210 had inhibited systemic anti-inflammatory effects of TGF-β over the 16-week study [37].