Similar to ALS, abnormal localization of Gle1, Nup62, and RanGAP1 (the binding partner of Nup358) in multiple models of HD and Nup62 in the hippocampus and neocortex of Alzheimer’s disease patients was previously reported [104,105,106]. The gene discussed is NUP62; the disease is early-onset autosomal dominant Alzheimer disease.