TNF and Sepsis: Due to (i) increased miR370-3p and TNF-α in sepsis mouse brains (Figure 1M,N and Figure 5A), (ii) TNF-α (and LPS) upregulated miR370-3p in neuron cells (Figure 7A), and (iii) the possible correlation of miR370-3p with cell energy status or the molecules that possibly correlated with energy pathways (Figure 5B and Figure 6), the elevated LPS and TNF-α in sepsis mice might upregulate miR370-3p in mouse brains that altered the neural functions through the interference on cell energy status.