Several of these filtered candidates were found to be secreted (C12orf49, COL10A1, FNDC4, ITLN2, MATN3, PDZD2, RS1, SCRG1, and ST6GALNAC5) making them potential candidate biomarkers useful for distinguishing IPF from pneumonitis. The gene discussed is SPRING1; the disease is idiopathic pulmonary fibrosis.