Monteleone et al. [42] investigated the expression of Col1a1 and Col3a1 in intestinal fibroblasts from patients with Crohn’s disease, finding that the expression and secretion of Col1a1 and Col3a1 were elevated in the presence of TGF-β1, and was reduced by the addition of FICZ. The gene discussed is COL3A1; the disease is Crohn disease.