GHRL and neoplasm: Significant reductions in tumour weight were demonstrated in GHSR1α knockdown SW480 mouse xenograft tumours compared to tumours from negative controls in a study of Liu et al. [61] Moreover, interesting research on the administration of exogenous AG or in the absence of endogenous ghrelin (Ghrl deletion) was performed in two mouse models of colon carcinogenesis—genetic (ApcMin/+ mice) and inflammation-associated (azoxymethane (AOM)/DSS).