Further, experiments with empagliflozin-treated myocardial infarction induced DM mice suggested increased glucose oxidation and ketone utilisation with increased myocardial levels of Sirt3 (mitochondrial deacetylation modification enzyme, which promotes effective oxidative metabolism) and antioxidant enzyme SOD2 (Superoxide Dismutase 2) [57]. The gene discussed is SOD2; the disease is myocardial infarction.