RORC and Huntington disease: Moreover, in the presence of HD/ASCs, the expression of Th17-related RORc (Figure 1D vs. Figure 2D) and IL-17AF secretion (Figure 5A,C vs. Figure 5B,D) were significantly enhanced in both types of activated target cells, showing that this effect is exerted directly by ASCs and not modified by other cell types present in PBMCs pool.