CCR2 and atherosclerosis: Other therapeutic approaches targeting monocytes in atherosclerosis context have been proposed, for example, by blocking C-C motif chemokine receptor 2 (CCR2)/C-C motif chemokine ligand 2 (CCL2)-mediated monocyte recruitment using small-interfering RNAs (siRNAs), monoclonal antibodies, CCR2 antagonists, pharmacological inhibition and monocyte chemoattractant protein 1 (MCP-1) inhibitors [111,112].