In the present study, we observed statistical differences between the NBD, BBD, and BC groups in the levels of adipocytokines, specifically leptin and adiponectin, and in metabolic indicators such as glucose, insulin, and HOMA IR for BBD in the lean and overweight-obese groups; and specifically, for the latter group, the significant differences were also for resistin and adipsin. This evidence concerns the gene LEP and breast cancer.