For the groups studied, adipsin values > 0.91 mg/mL, insulin levels above 2.6 mU/mL, HOMA IR > 0.78, and visfatin levels above 1.18 ng/mL posed a risk of developing BBD in women with NBD as high as OR:75 (p = 0.000) and for developing BC in women with NBD OR: 56 (p = 0.000). The gene discussed is NAMPT; the disease is breast cancer.