These results demonstrate that upregulated EZH2 can support tumor growth and further imply that it is a crucial regulator in carcinogenesis for 15 types of cancer, including BLCA, BRCA, CESC, CHOL, COAD, GBM, HNSC, KIRC, KIRP, LIHC, LUAD, LUSC, READ, STAD, and UCEC. Here, EZH2 is linked to cancer.