miR-1 inhibits tumor growth and metastasis by simultaneously targeting multiple genes: CDK4 (cyclin-dependent kinase 4), TWF1 (twinfilin actin-binding protein 1), WASF2 (WAS protein family, member 2), CNN3 (calponin 3, acidic), CORO1C (coronin, actin binding protein, 1C) and TMSB4X (thymosin beta 4, X-linked) [39]. Here, CNN3 is linked to neoplasm.