Individuals with IA-2A are at increased risk for T1D progression [13], and the IA-2A-associated genes 1q23/FCRL3 and 11q13/RELA are assumed as candidates for early screening of clinical onset of T1D [12,14], while IFIH1 is negatively associated with IA-2A [10]. This evidence concerns the gene FCRL3 and type 1 diabetes mellitus.