Since then, at least 20 susceptibility genes have been detected to have germline mutations, such as NF1 (neurofibromatosis type 1), TMEM127 (transmembrane protein 127), FH (fumarate hydratase), VHL (Von Hippel-Lindau), and others [2,3]. This evidence concerns the gene TMEM127 and neurofibromatosis type 1.