In GEO datasets, CDKN2A showed a significantly higher expression in ccRCC tissues (GSE40435: log2(fold change) = 0.23, p = 3.76 × 10−19; GSE53757: log2(fold change) = 2.05, p = 5.02 × 10−27, Supplementary Table S1) while DLAT, FDX1 and LIAS were significantly downregulated in their expression levels in ccRCC tissues (Figure 5A,B). This evidence concerns the gene FDX1 and nonpapillary renal cell carcinoma.