Shown in Figure 8, the expression levels of four genes (CDKN2A, DLAT, FDX1 and LIAS) varied in different pathologic stages and histological grades of ccRCC, with the exception of DLD, which did not show any statistical difference across histological grades (p = 0.063, Figure 8B). This evidence concerns the gene CDKN2A and nonpapillary renal cell carcinoma.