The present research supported the roles of hsa_circ_0006692’s in promoting NSCLC tumor progression via the enhancement of cell migration, invasiveness, and their expression of the proliferative ability with associated gene PCNA, CCND1, and anti-apoptosis BCL-2, EMT associated genes CDH2, MMP7, and VIMENTIN. The gene discussed is CDH2; the disease is neoplasm.