IGF2 and posterior cortical atrophy: Several studies have identified genes that have a significant role in the onset and development of PCa, such as forkhead box A1 (FoxA1) [19], kallikrein-related peptidase 3 (KLK3) [20], insulin-like growth factor 2 (IGF2) [21], and phosphatase and tensin homolog (PTEN) [22].