For example, Han et al. suggested that plasma miR-148a is a possible biomarker for HCC screening [26]; miR-107 suppresses the proliferation of HCC cells by targeting HMGA2 [27]; the dysregulation of miR-100 is an early event in HCC progression [28], and its inactivation contributes to hepatocarcinogenesis in vivo [29]. The gene discussed is HMGA2; the disease is hepatocellular carcinoma.