Specifically, 16.8% of DC patients carrying the MMP14 rs1042704 AA genotype first symptoms of DC were observed at less than 56 years of age, compared to 3.2% of noncarriers (OR 2.160; 95% CI: 2.160–7.824; p = 0.024). The gene discussed is MMP14; the disease is dyskeratosis congenita.