The fusions reported in endometrial stromal sarcomas (ESS) include JAZF1-SUZ12, YWHAE-FAM22, ZC3H7-BCOR, MBTD1-CXorf67, and fusions of PHF1 with JAZF1, EPC1, and MEAF6 [46]. The gene discussed is YWHAE; the disease is endometrioid stromal sarcoma.