Thus, inborn errors from cortisol biosynthesis such as StAR-defect, P450 side chain cleavage defect, 3β-hydroxysteroid dehydrogenase deficiency, 21-hydroxylase deficiency, 11-hydroxylase deficiency, 17-hydroxylase/17,20 lyase deficiency, and Smith Lemli Opitz syndrome could be excluded. The gene discussed is STAR; the disease is Smith-Lemli-Opitz syndrome.