Thus, inborn errors from cortisol biosynthesis such as StAR-defect, P450 side chain cleavage defect, 3β-hydroxysteroid dehydrogenase deficiency, 21-hydroxylase deficiency, 11-hydroxylase deficiency, 17-hydroxylase/17,20 lyase deficiency, and Smith Lemli Opitz syndrome could be excluded. This evidence concerns the gene CYP2B6 and classic congenital adrenal hyperplasia due to 21-hydroxylase deficiency.