MAPT and early-onset autosomal dominant Alzheimer disease: Future studies might use neuroimaging techniques, which could help to understand whether the clinical improvement reported here is associated with functional or maturational changes at the level of a specific network, as has been shown in Alzheimer’s disease, where the improvement in clinical manifestation after tPBM treatment was associated with a reduction in tau and beta-amyloid levels (Chao, 2019) [35].