The EGCG induction of protein degradation has been demonstrated in previous studies; EGCG mediated the protein kinase C- and proteasome-dependent degradation of Bad [56] in neuronal cells and prevented the aggregation of pulmonary-fibrosis-associated mutant surfactant protein A2 via a proteasomal degradation pathway [57]. The gene discussed is BAD; the disease is pulmonary fibrosis.