NFKB1 and cancer: As reviewed by Wang et al. [97], there are many broad-spectrum drugs, such as proteasome inhibitors (e.g., Bortezomib, Carfilzomib), histone deacetylase inhibitors (e.g., Vorinostat, Romidepsin), and natural compounds (e.g., curcumin, resveratrol) that block constitutive NF-κB activity and are the subject of various cancer clinical trials, including current BCa clinical trials (NCT04265872, NCT01142401, NCT02257476, NCT00616967, NCT03742245, NCT02393794, NCT03980509).