CD4 and neoplasm: The CD4/CD8 ratio was observed to be higher in miR-18a high tumors (p = 0.009) (Figure 2H) accompanied by an increased proportion of exhausted CD8 + T cells (p < 0.0001) (Figure 2I), induced Treg (iTreg) population (p = 0.01) (Figure 2J), dendritic cell population (p = 0.03) (Figure 2K), and decreased proportions of anti-tumor response eliciting Th17 cells (p < 0.0001).