The effects of Class I HDAC inhibitors on bronchiolar basal cells and the aberrant bronchiolization process in IPF remain to be determined, which would help to clarify the role of the eminent upregulation of all Class I HDACs in basal cells, Clara cells as well as FOXJ1 expressing the bronchial cells of IPF lungs. This evidence concerns the gene FOXJ1 and idiopathic pulmonary fibrosis.