CDKN1A and idiopathic pulmonary fibrosis: In accordance, it could be demonstrated that the pan-HDAC inhibitor panobinostat (LBH589), an FDA-approved drug for the treatment of multiple myeloma since 2015 [229], reduced proliferation, collagen-I biosynthesis, and anti-apoptotic genes in IPF fibroblasts in vitro, with concomitant induction of p21Cip1 and ER stress-mediated apoptosis [165].