In addition to the inactivation of Class I HDAC activity, panobinostat strongly inhibited HDAC6 activity (and also, therefore, with high probability, its profibrotic signalling) in IPF fibroblasts [249], which is in accordance with studies of its marvellous efficacy in various cancers [303]. This evidence concerns the gene HDAC6 and idiopathic pulmonary fibrosis.