CXCL10 and idiopathic pulmonary fibrosis: Similar observations they made for the CXCL10 gene, which is suppressed in IPF fibroblasts as well due to insufficient histone H3/H4 acetylation and repressive histone H3 hypermethylation at its promoter as a result of decreased recruitment of HATs but increased recruitment of Class I HDAC-containing transcriptional repressor complexes in IPF fibroblasts [247].