Consistent with this, chromosomal duplications or deletions of 16p11.2, which includes the MAPK3 gene encoding for ERK1, or a microdeletion on chromosome 22, which contains the MAPK1 gene coding for ERK2, are commonly found to be associated with neurodevelopmental disorders and ASD [20,21,22]. The gene discussed is MAPK3; the disease is neurodevelopmental disorder.