Several oncogenes are involved in the pathogenesis of NSCLC: epidermal growth factor receptor (EGFR), B-Raf (BRAF), anaplastic lymphoma receptor tyrosine kinase (ALK), MET proto-oncogene (MET), and c-ros oncogene 1 (ROS1) [4]. The gene discussed is ALK; the disease is non-small cell lung carcinoma.