TMUB1 and early-onset autosomal dominant Alzheimer disease: In recent research, hypoxia-induced miR-210 was shown to target synaptic function genes (GRINA, TMUB1, and AP2S1), plasticity genes (ACTB), Alzheimer’s disease genes (APOE), and genes implicated in MAPK/VEGF and OXPHOS signaling pathways [34].