The European Society of Cardiology recommends NT-proBNP as an initial diagnostic test in all patients presenting with symptoms suggestive of new onset or worsening HF, with a cut-off of <125 pg/mL being used to rule out HF in patients < 50 years old with mild symptoms in the non-acute setting and <300 pg/mL in the acute setting with shortness of breath [4,5]. Here, NPPB is linked to hydrops fetalis.