ABCB11 and cholestasis: Extreme prematurity with severe anoxo-ischemia and long term parenteral nutrition. Neonatal cholestasis. Deceased during neonatal period (multiorgan failure).Post mortem LB: panlobular dissecting fibrosis, ductopenia, hepatocellular cholestasis, disseminated intravascular coagulopation. Possible consequences of a submassive destruction of liver parenchyma.Family history of liver disease (mother: ICP; twin brother: TNC (carrying only ABCB11 variant); healthy older sister (same genotype): asymptomatic vesicular lithiasis).