In our previous study, we also found, among cytokines with high diagnostic values (AUC > 0.7), to diagnose ESSIC type 2 IC/BPS from controls, RANTES, MIP-1β, and IL-8 were of higher sensitivity, and MCP-1, CXCL10, and eotaxin were of higher specificity. The gene discussed is CXCL10; the disease is Bartsocas-Papas syndrome 1.