It has three attributes that recommend its use during cancer treatment: (1) it inhibits Hedgehog (Hh) signaling [189,190,191,192,193], (2) it inhibits 5-lipoxygenase (5-LO) [193,194,195,196], and (3) it inhibits the P-gp efflux pump [188,197,198,199]. Here, PGP is linked to cancer.