RNA-seq has since allowed the characterization of novel fusion genes such as CIC-NUTM1 [11], TFCP2-rearranged [12], EWSR1-SSX1 [13], as well as the identification of NTRK-rearranged sarcomas [14] or NRG1-fused sarcomas [15]. This evidence concerns the gene EWSR1 and sarcoma.