A subset of 13 prognostic genes was found to be shared by LGG and GBM, 10 of which (DRD1, HTR1E, HTR3B, GABRA1, GABRA4, GABRB2, GABRG2, GRIN1, GRM7, and ADRA1B) were associated with favorable prognostics for LGG, but were unfavorable for GBM. The gene discussed is HTR3B; the disease is glioblastoma.