For all the 10-NTR genes, the expression levels tended to decrease progressively as the grade increased from grade II (low-grade glioma, N = 515 for TCGA and N = 625 for CGGA) to IV (glioblastoma multiforme, N = 152 for TCGA and N = 338 for CGGA), as shown in Figure 5. Here, NTSR1 is linked to central nervous system cancer.