Atef et al. found that estrogen, progesterone, and androgen receptors were positive in 56%, 50%, and 64% of 50 laryngeal cancer patients, respectively; also, the expressions of estrogen and progesterone receptors were significantly higher, whereas that of androgen receptor was lower, in patients with aggressive clinical and pathological manifestations [48]. The gene discussed is PGR; the disease is laryngeal carcinoma.