BRCA1 and neoplasm: Using this system and other candidate biomarkers, including mutations in other HRR genes (including BR IP1, CDK12, RAD54L, RAD51B, ATM, FANCA, FANCD2, FANCL, RAD51C, RAD52, and XRCC) and BRCA1 promoter methylation, tumor samples from olaparib maintenance monotherapy (study 19 [22]) were analyzed [23].