AKT1 and breast carcinoma: We used nine driver genes identified in this study (TP53, ESR1, GATA3, KMT2C, NCOR1, AKT1, NF1, RIC8A, RB1) as well as additional genes frequently altered in breast cancer (PTEN, PIK3CA, BRCA1, BRCA2, ERBB2, EGFR).