As a neoplasm involving the HSC compartment, the KIT D816V (and other KIT) mutations can be found in both neoplastic MCs and CD34+ BM HSC, as well as in other myeloids (e.g., neutrophils [9,72,73,74], monocytes [9,70,72,73,74], basophils [70,72,74] and/or eosinophils [9,74]) and/or lymphoid (e.g., T and B lymphocytes [9,70,73,74]) cells. The gene discussed is KIT; the disease is neoplasm.