CD3E and enteropathy-associated T-cell lymphoma: Given that development of EATL is seen almost exclusively in cases with >20% atypical T-cells by flow cytometry [181], the cut-off criterion between RCD1 and RCD2 is defined as >20% of phenotypically atypical (sCD3-, CD3ε+ CD8−) T-cells by flow cytometry [181] and >50% of such T-cells by immunohistochemistry [182,183].