FLT3 and acute myeloid leukemia: Moreover, considering that the ETP cases are allocated into the high-risk arm, the MRD detection using FLT3-ITD in association with FCM methodology as well as in children with AML [33] should allow us to characterize those cases for whom the hematopoietic stem cell transplantation could be avoided or chosen wisely, thus introducing novel drugs with promising efficacy along the induction phase or even the entire duration of the treatment plan.