PROM1 and cancer: Smiley et al. [180] describe poly(styrene-b-ethylene oxide)-PLGA polymeric nanomicelles coloaded with temozolomide and idasanutlin (RG7388, an inhibitor of mouse double minute 2, MDM2) and decorated with an aptamer for CD133, which is a surface glycoprotein overexpressed by cancer stem cells in glioblastoma multiforme.