PRPS2 and acute lymphoblastic leukemia: A similar study, assessing 103 pediatric ALL triplets (87 BCP and 16 T-cell ALL), observed that relapse-specific somatic alterations were enriched in 12 genes (NR3C1, NR3C2, TP53, NT5C2, FPGS, CREBBP, MSH2, MSH6, PMS2, WHSC1, PRPS1, and PRPS2), all of which were involved in the drug response.