To investigate whether the high frequency of p62/Nrf2high tumor lesions in NEMOLPC-KO p62ΔEx2-5 mice could be due to p62ΔEx2-5 mutant driving a stronger Nrf2 activation compared to full-length p62, we compared the expression of NQO1 in liver lysates of 1-year-old NEMOLPC-KO and NEMOLPC-KO p62ΔEx2-5 mice. This evidence concerns the gene SQSTM1 and neoplasm.