Considering tumor size change at best response, the miR-625-5p Low/PD-L1 ≥ 50% group showed a mean reduction in tumor size of 34.45% (median 33.5%), whereas the other three groups showed a mean increase in tumor size ranging from 8.62% (median 13.5%) to 32.13% (median 30%) (p < 0.001) (Figure 5). Here, CD274 is linked to neoplasm.