TP53 and myelodysplastic syndrome: However, the results of the primary data cut from the phase 3 trial comparing azacitidine + eprenetapropt vs. azacitidine monotherapy in patients with TP53-mutated higher-risk MDS, a biologically similar disease, demonstrated no difference in CR, the primary endpoint, between groups (33.3% vs. 22.2%, respectively; p = 0.13).