In breast cancer MCF-7 cells, EMD638683, GSK650394, and testosterone albumin conjugate induced strong apoptotic response and caspase 3 activation (p < 0.01), enhanced radiation-induced cell growth control (p < 0.001) and induced late FAK and AKT dephosphorylation (p < 0.01) [57]. Here, AKT1 is linked to breast cancer.